Journal of APPLIED BIOMEDICINE
ISSN 1214-0287 (on-line)
ISSN 1214-021X (printed)

Volume 1 (2003), No 2, p 93-97




Are nucleoli participating in programmed cell death

Karel Smetana

Address: Karel Smetana, Institute of Hematology and Blood Transfusion, U nemocnice 1, 128 20 Praha 2, Czech Republic
karel.smetana@uhkt.cz

Received 11th December 2002.
Published online 4th March 2003.

Full text article (pdf)

SUMMARY
Despite numerous publications on nucleoli, their participation in terminal maturation and programmed cell death have not been studied extensively. On the other hand, some observations clearly indicate that terminal maturation and programmed cell death are accompanied by marked nucleolar changes which reflect the cessation of nucleolar biosynthetic activities. In addition, nucleolar changes in the course of terminal maturation may precede programmed cell death.

KEY WORDS
nucleolus; erythrocytic and granulocytic precursors; terminal maturation; programmed cell death


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CITED

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