ISSN 1214-0287 (on-line)
ISSN 1214-021X (printed)

Volume 1 (2003), No 2, p 77-84

Why do circadian biorhythms age?

Josef Berger

Address: Josef Berger, Institute of Biophysics and Medical Engineering, Faculty of Health and Social Studies, Branisovska 31, 370 05 Ceske Budejovice, Czech Republic

Received 26th February 2003.
Published online 19th March 2003.

Full text article (pdf)

Circadian biorhythms change with age and such changes are caused by the loss of both the time and the space structure. These alterations of biorhythms are associated with poor health and the end of life but we do not know the extent to which they represent cell clock system injury. It seems that ageing of biorhythms in mammals, i.e. including humans, is caused by the ability of suprachiasmatic nuclei to drive oscillations in other tissues. Social synchronization extending photic stimuli, which diminishes during degeneration of nerve and optic system, enhances the quality of life and therefore further studies of the influence of health and social care systems on circadian rhythms could contribute to the lengthening of life.

ageing; rhythm; regulation; synchronizer; quality of life

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