We evaluate the possibility of using insects as a haematological biomodel and we test phytoestrogen isoflavanoid, genistein, in Schistocerca gregaria, Periplaneta americana and Dysdercus cingulatus. Various reactions of haemocytes were found in these three species, both stimulation and inhibition of haemocyte concentration. The observed data reflected well the possible effects of soy products described in published studies on human subjects and it seems that future studies on the sensitivity of insect haemocytes could lead to an alternative haematological biomodel.
alternative biomodel; haemocyte; genistein; pre-clinical prediction
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