Journal of APPLIED BIOMEDICINE
ISSN 1214-0287 (on-line)
ISSN 1214-021X (printed)

Volume 2 (2004), No 4, p 179-185




Chronohaematology

Josef Berger

Address: Josef Berger, Faculty of Health and Social Studies, University of South Bohemia, 370 05 Ceske Budejovice, Czech Republic
berger@jcu.cz

Received 18th August 2004.
Revised 20th October 2004.
Published online 22nd November 2004.

Full text article (pdf)

SUMMARY
Rhythmic changes in a number of haematological characteristics have been described in many published papers during the 20th and at the beginning of the 21st century. The best known are circadian rhythms, which are mostly correlated with the light/dark regime, inducing rhythmic changes in levels of melatonin, synchronised by a suprachiasmatic nucleus and the retinohypothalamic input. These circadian rhythms in men and diurnal animals have an inverse relationship to rhythms in nocturnal beings. Some haematological rhythms are modified by other synchronisers. Knowledge of circadian rhythms in haematological characteristics is important for both the faultless clinical interpretation of laboratory data and the search for mechanisms participating in rhythm regulation.

KEY WORDS
circadian rhythm; blood cell; haemopoiesis; clinical significance; synchronization


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