ISSN 1214-0287 (on-line), ISSN 1214-021X (printed)
J Appl Biomed
Volume 8 (2010), No 2, p 111-116
DOI 10.2478/v10136-009-0009-5

Kinetics of hydrolysis of organophosphate soman by cationic surfactant Resamin AE

Jiri Cabal, Jitka Micova, Kamil Kuca

Address: Jiri Cabal, Department of Toxicology, Faculty of Military Health Sciences, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
cabal@pmfhk.cz

Received 20th August 2009.
Published online 15th January 2010.

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SUMMARY
This experiment tested the reactivity of the cationic surfactant Resamin AE [N-(2-hydroxyethyl)-N-(2-hydroxy-4-oxa(C14÷22-alkyl))-N,N-dimethylammonium chloride] with organophosphonate soman. It was confirmed that soman is incorporated in the micelle of Resamin AE and that the hydroxyl group or Resamin AE supports the hydrolysis of this organophosphonate. A further increase in reactivity was achieved by the addition of hydrogen peroxide into the reaction mixture. In contrast, if the concentration of neutral salts was increased, a decrease in the velocity of the hydrolysis was obtained. The hydrolytic efficacy of Resamin AE was also compared with that of hexadecyldimethyl-(2-hydroxyethyl)-ammonium bromide. Resamin AE appeared to be a more efficacious hydrolytic agent than other similar compounds due to its advantageous chemical structure.

KEY WORDS
cationic surfactants; micellar catalysis; soman; decontamination; Resamin AE


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CITED

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