J Appl Biomed 1:161-168, 2003 | DOI: 10.32725/jab.2003.030

Effects of genistein on insect haemocytes

Josef Berger1,*, Sylvia Walczysko2, Jitka Pávková2, Herwig O. Gutzeit3
1 Faculty of Health and Social Studies South Bohemian University in České Budějovice, Czech Republic
2 Faculty of Biology South Bohemian University in České Budějovice, Czech Republic
3 Institute of Zoology Technical University in Dresden, Germany

We evaluate the possibility of using insects as a haematological biomodel and we test phytoestrogen isoflavanoid, genistein, in Schistocerca gregaria, Periplaneta americana and Dysdercus cingulatus. Various reactions of haemocytes were found in these three species, both stimulation and inhibition of haemocyte concentration. The observed data reflected well the possible effects of soy products described in published studies on human subjects and it seems that future studies on the sensitivity of insect haemocytes could lead to an alternative haematological biomodel.

Keywords: alternative biomodel; haemocyte; genistein; pre-clinical prediction

Received: June 16, 2003; Published: July 31, 2003  Show citation

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Berger J, Walczysko S, Pávková J, Gutzeit HO. Effects of genistein on insect haemocytes. J Appl Biomed. 2003;1(3):161-168. doi: 10.32725/jab.2003.030.
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