J Appl Biomed 4:171-178, 2006 | DOI: 10.32725/jab.2006.019

Expectations of biologically active compounds of the genus Magnolia in biomedicine

Jiří Patočka1,*, Jiří Jakl2, Anna Strunecká3
1 Department of Radiology and Toxicology, Faculty of Health and Social Studies, University of South Bohemia, České Budějovice, Czech Republic
2 Department of Dendrology and Forest Tree Breeding, Faculty of Forestry and Environment of the Czech University of Agriculture Prague, Czech Republic
3 Department of Physiology and Developmental Biology, Faculty of Science, Charles University, Prague, Czech Republic

Magnolia bark is a highly aromatic herbal material obtained from Magnolia officinalis (and other species) of the family Magnoliaceae. In traditional oriental herbal medicine, particularly Chinese medicine, this drug is used for many purposes, especially as a mild tranquillizer. The principal active compounds are the biphenol compounds, magnolol and honokiol, together with other biologically active compounds, which exert numerous and diverse pharmacological actions. Recent research has produced further evidence for the mechanism of their anti-inflammatory, anti-oxidant, antimicrobial, and antitumour activities, and these will be outlined in this review.

Keywords: herbal tranquillizer; honokiol; Magnolia; magnolol; obovatol; pharmacology

Received: July 18, 2006; Published: July 31, 2006  Show citation

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Patočka J, Jakl J, Strunecká A. Expectations of biologically active compounds of the genus Magnolia in biomedicine. J Appl Biomed. 2006;4(4):171-178. doi: 10.32725/jab.2006.019.
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