Journal of Applied Biomedicine, 2008 (vol. 6), issue 3

Original Research Article

Changes in CD4+ cell count, lipid profile and liver enzymes in HIV infection and AIDS patients

Palanisamy Pasupathi, Govindaswamy Bakthavathsalam, Ganesan Saravanan, Ayyaswamy Devaraj

J Appl Biomed 6:139-145, 2008 | DOI: 10.32725/jab.2008.017  

This study was designed to find the correlation between changes in CD4+ cell count, lipid profile and liver marker enzymes in HIV-infected and AIDS patients. The study population consisted of 150 subjects, age and sex-matched and divided into three groups [control subjects (n=50), HIV infected (n=50) and AIDS patients (n=50)]. We observed a significant reduction in CD4+ cell count in HIV/AIDS patients when compared to control subjects. Serum levels of total cholesterol, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were found to be decreased significantly in HIV/AIDS patients when...

Electro-acupuncture in the dog: diagnostic evaluation points

Elisabetta Giudice, Silvia Galia, Claudia Giannetto

J Appl Biomed 6:147-152, 2008 | DOI: 10.32725/jab.2008.018  

The aim of this study was to identify electro-acupuncture points in the dog and to evaluate diagnostic aspects of the application of electro-acupuncture in veterinary medicine. For this purpose, we used four crossbred dogs affected by different diseases and four healthy dogs. In all animals, the conductance was measured by using electro-acupuncture according to Voll, "EAV" GOLD. Measurement carried out in the four ill dogs showed conductance values higher (70 SU) or lower (30-40 SU) than that observed in healthy dogs (45-60 SU). Our results showed that the measurement of conductance in the acupoint along the Bladder meridian might be considered as...

Calcium channel blockade alleviates brain injury induced by long term exposure to an electromagnetic field

Sahar El-Swefy, Hala Soliman, Magdy Huessein

J Appl Biomed 6:153-163, 2008 | DOI: 10.32725/jab.2008.019  

This study aimed to examine the effects of short and long term exposures to 81 mG EMF intensity. It focused on the roles of ROS, Ca2+ and calcium channel blocker (CCB) on the rat brain. Rats were exposed to 81 mG EMF intensity at the mobile phone base station for one and four weeks (2 hr/day, EMF exposed group). Another group of rats was pretreated with CCB (amlodipine 20 mg/kg) for four weeks and similarly exposed to EMF (EMF + amlodipine group). Sham exposed and amlodipine control groups were used. At the end of the study, Ca2+ as well as pro-inflammatory and oxidative stress markers were measured. Immunohistochemical staining...

Reviews

Silver or silver nanoparticles: a hazardous threat to the environment and human health?

Nagender Reddy Panyala, Eladia María Peña-Méndez, Josef Havel

J Appl Biomed 6:117-129, 2008 | DOI: 10.32725/jab.2008.015  

Nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles that measure in nanometers. These nanomaterials are already having an impact on health care. Now-a-days we are using nanoproducts in various fields. Of these, silver nanoparticles are playing a major role in the field of nanotechnology and nanomedicine.Their unique size-dependent properties make these materials superior and indispensable as they show unusual physical, chemical and biological properties. Silver nanoparticles have potential antimicrobial activity towards many pathogenic microbes. Along with this antimicrobial activity, silver nanoparticles...

Sleep-wake cycle, aging and cancer

Farhad F. Shadan

J Appl Biomed 6:131-138, 2008 | DOI: 10.32725/jab.2008.016  

Disruptions in sleep-wake patterns have been linked to a variety of health problems, including an increase risk for obesity, type II diabetes, and hypertension. The link to increased risk of malignancy and premature aging is less clear, however. This manuscript reviews current epidemiological and experimental evidence linking alterations in sleep-wake patterns to malignancy and premature aging. Epidemiological evidence suggests that alterations in sleep-wake patterns (e.g.; night-shift or rotating-shift work) are associated with increases in leukemia, endometrial, breast, prostate, and colorectal cancers. Excessive long or short sleep duration is associated...