J Appl Biomed 1:93-97, 2003 | DOI: 10.32725/jab.2003.014

Are nucleoli participating in programmed cell death? (MINI-REVIEW AND RECENT OBSERVATIONS)

Karel Smetana
Clinical Department, Institute of Hematology and Blood Transfusion, Prague, Czech Republic, Department of Pharmacology, Baylor College of Medicine, Houston, USA

Despite numerous publications on nucleoli, their participation in terminal maturation and programmed cell death have not been studied extensively. On the other hand, some observations clearly indicate that terminal maturation and programmed cell death are accompanied by marked nucleolar changes which reflect the cessation of nucleolar biosynthetic activities. In addition, nucleolar changes in the course of terminal maturation may precede programmed cell death.

Keywords: nucleolus; erythrocytic and granulocytic precursors; terminal maturation; programmed cell death

Received: December 11, 2002; Published: July 31, 2003  Show citation

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Smetana K. Are nucleoli participating in programmed cell death? (MINI-REVIEW AND RECENT OBSERVATIONS). J Appl Biomed. 2003;1(2):93-97. doi: 10.32725/jab.2003.014.
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