J Appl Biomed 3:129-131, 2005 | DOI: 10.32725/jab.2005.016

Population genetics of 11 nuclear and 1 mitochondrial short tandem repeat loci in a population of South Bohemia, Czech Republic

Tomáš Vaněček1,3, Pavel Trubač2,3, František Vorel2, Miroslav Šíp4,*
1 Sikl`s Department of Pathology, Charles University Hospital, Plzeň, Czech Republic
2 Department of Forensic Medicine, University Hospital, České Budějovice, Czech Republic
3 Faculty of Biological Science, University of South Bohemia, České Budějovice, Czech Republic
4 Faculty of Health and Social Studies, University of South Bohemia, České Budějovice, Czech Republic

A population study on 11 nuclear and 1 mitochondrial short tandem repeats (STR) (CSF1PO, TPOX, THO1, F13A01, FESFPS, vWA, D16S539, D7S820, D13S317, LPL, F13B and mitochondrial (CA)n repeat (mtCA)) was performed, and allele frequencies together with other forensic genetics characteristics, were estimated from a sample of 111 - 253 unrelated individuals living in the area of South Bohemia, Czech Republic. All loci, except F13B, meet Hardy-Weinberg expectations. Significant differences of allele frequencies were found in three (vWA, D16S539 and F13B) or two loci (vWA, D16S539) when compared with reference or known Czech data, respectively. An allele frequencies comparison of the mitochondrial marker shows significant differences only in the case of the African population.

Keywords: short tandem repeat; population data; GenePrint STR Kit; mitochondrial CA repeat polymorphism; Czech Republic

Received: February 28, 2005; Revised: April 12, 2005; Published: July 31, 2005  Show citation

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Vaněček T, Trubač P, Vorel F, Šíp M. Population genetics of 11 nuclear and 1 mitochondrial short tandem repeat loci in a population of South Bohemia, Czech Republic. J Appl Biomed. 2005;3(3):129-131. doi: 10.32725/jab.2005.016.
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