J Appl Biomed 8:111-116, 2010 | DOI: 10.2478/v10136-009-0009-5

Kinetics of hydrolysis of organophosphate soman by cationic surfactant Resamin AE

Jiří Cabal^1,*, Jitka Míčová¹, Kamil Kuča^1,2

¹ Department of Toxicology, Faculty of Military Health Sciences, Hradec Králové, Czech Republic

² Center of Advanced Studies, Faculty of Military Health Sciences, Hradec Králové, Czech Republic

This experiment tested the reactivity of the cationic surfactant Resamin AE [N-(2-hydroxyethyl)-N-(2-hydroxy-4-oxa(C14/22-alkyl))-N,N-dimethylammonium chloride] with organophosphonate soman. It was confirmed that soman is incorporated in the micelle of Resamin AE and that the hydroxyl group or Resamin AE supports the hydrolysis of this organophosphonate. A further increase in reactivity was achieved by the addition of hydrogen peroxide into the reaction mixture. In contrast, if the concentration of neutral salts was increased, a decrease in the velocity of the hydrolysis was obtained. The hydrolytic efficacy of Resamin AE was also compared with that of hexadecyldimethyl-(2-hydroxyethyl)-ammonium bromide. Resamin AE appeared to be a more efficacious hydrolytic agent than other similar compounds due to its advantageous chemical structure.

Keywords: cationic surfactants; micellar catalysis; soman; decontamination; Resamin AE

Received: August 20, 2009; Published: July 31, 2010  Show citation