J Appl Biomed 16:289-300, 2018 | DOI: 10.1016/j.jab.2018.08.001

Phytochemical analysis and assessment of antioxidant and antimicrobial activities of some medicinal plant species from Egyptian flora

Rania Al-Tohamya,b, Sameh Samir Alia,b,*, Khalil Saad-Allahb, Mervat Fareedc,d, Asmaa Alie, Anwer El-Badryb, Nessma Ahmed El-Zawawyb, Jian Wua, Jianzhong Suna,*, Guang-Hua Maof, Parveen Fatemeh Rupania
a Biofuels Institute, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China
b Botany Department, Faculty of Science, Tanta University, Tanta, Egypt
c Department of Home Economic, Faculty of Specific Education, Tanta University, Tanta, Egypt
d Department of Biology, Faculty of Science, Taif University, Taif, Saudi Arabia
e Abbasia Chest Hospital, Ministry of Health and Population, Cairo, Egypt
f School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, China

Plants offer unlimited source of bioactive compounds that have tremendous applications in pharmaceutical industry. To find new sources of antioxidants and antimicrobial agents against pan-drug resistant (PDR) pathogens of skin burn infections, methanolic extracts of nine Egyptian plants were evaluated. Total phenolic content varied from 19.48 to 65.48mg GAE/g dry weight (dw). Total flavonoid content varied from 2.90 to 11.09mg QE/g dw, while total alkaloid content varied from 18 to 60mg/g dw. Suaeda vermiculata, Varthemia candicans and Arthrocnemum glaucum showed the highest content of phenolics, flavonoids and alkaloids, respectively. The results of antioxidant (DPPH assay) activity were varied to a great extent and Varthemia candicans (90.6%) and Suaeda vermiculata (90.5%) showed the highest antioxidant activities. Antimicrobial activity was assessed against four PDR bacterial and fungal strains; namely Staphylococcus aureus, Klebsiella pneumoniae, Candida albicans and Aspergillus flavus. Among all examined extracts, Salsola vermiculata and Suaeda vermiculata showed significant antimicrobial activity. The fatty acid composition of Salsola vermiculata and Suaeda vermiculata leaf extracts was detected using GC-MS analysis. Overall, Salsola vermiculata and Suaeda vermiculata could be used as an alternative source for the exploration of new antioxidant and antimicrobial agents that are potentially valued for food and biomedical applications.

Keywords: Antioxidant; Antimicrobial; Salsola vermiculata; Suaeda vermiculata; Pan-drug resistance; Burn infections

Received: February 2, 2018; Revised: July 20, 2018; Accepted: August 20, 2018; Published: November 1, 2018  Show citation

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Al-Tohamy R, Ali SS, Saad-Allah K, Fareed M, Ali A, El-Badry A, et al.. Phytochemical analysis and assessment of antioxidant and antimicrobial activities of some medicinal plant species from Egyptian flora. J Appl Biomed. 2018;16(4):289-300. doi: 10.1016/j.jab.2018.08.001.
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