Journal of Applied Biomedicine, 2003 (vol. 1), issue 1

Original Research Article

Possibilities of current use of non-invasive laser therapy and systemic enzymotherapy in stomatology

Leoš Navrátil, Blanka Navrátilová, Jiří Knížek, Zuzana Erösová, Hana Fikáčková, Jaroslava Kymplová

J Appl Biomed 1:13-19, 2003 | DOI: 10.32725/jab.2003.003

There are no doubts about the benefits of non-invasive laser therapy in treating surgical wounds, thanks to its anti-inflammatory, stimulating and analgesic effects. Systemic enzymotherapy is particularly employed due to its thrombolytic, fibrinolytic and antiedema effects. Concurrent use of the two above mentioned treatment modalities exerts a synergistic action. Thus, it is possible to reduce the persistence of the pain as well as the duration of the post-operation period after surgical interventions in the mouth cavity at a statistically highly significant level. Thus, this approach can be recommended for achieving a favourable outcome in most post-operation...

Biomedical and medical education within a digital society

Josef Berger

J Appl Biomed 1:21-27, 2003 | DOI: 10.32725/jab.2003.004

Digital computers, which elevate the capacity of both individuals and human society, spread their possibilities widely in education. Software supports the teaching of physiology, anatomy, radiology, nursing, laboratory sciences and other fields of medicine. Existing learning programmes were assigned to drill and examined. The extension of the capacity of software graphics and penetration into research and practice makes it possible to use original documents and images and, therefore, to construct virtual reality which elevates effectiveness in facility training and the teaching of a creative approach among students. The Internet has been a major communication...

Scientific research: methodological guidelines for the social sciences

Paul H. Möller, Vladimír Vurm, Petr Petr

J Appl Biomed 1:29-40, 2003 | DOI: 10.32725/jab.2003.005

Scientific research is one of a number of roles in the role repertoire of students and academics. However, to successfully fulfil this role, one has to understand the meaning of various concepts e.g. science, scientific research, scientific method and theory. In describing these concepts the meaning of the goals of science and scientific research, as well as the method of composing a research proposal all become clearer.

Physics for radiological workers

Přemysl Záškodný

J Appl Biomed 1:41-48, 2003 | DOI: 10.32725/jab.2003.006

The graduate of the undergraduate course "Imaging Methods and Applications of Ionizing Radiation" can work as a Radiological assistant (e.g. at the hospitals), a Radiological technologist (e.g. at the nuclear power stations) or a Radiological specialist (e.g. for the municipal authorities). The profile of the graduate will be elaborated on the basis of analytical-synthetic modelling. Analytical-synthetic model of the profile enables to find out the role of physics for radiological workers in the framework of the relevant undergraduate course. It will be presented by means of several illustrations of partial topics of physics for radiological workers.

Review Article

Excitotoxicity and the putative involvement of excitatory amino acids in neurodegenerative diseases

André Nieoullon, Laurence Had-Aissouni, Lydia Kerkerian-le Goff

J Appl Biomed 1:1-5, 2003 | DOI: 10.32725/jab.2003.001

Excitatory amino acids (EAA) represent major brain neurotransmitters. They are present in numerous neuronal systems and thus are involved in almost all aspects of normal and pathological brain activity. Changes in EAA transmission have been associated with the functional impairments characterizing major neurological disorders, including epilepsy and schizophrenia. There is also a suspicion that EAA systems underlie the neuronal death associated not only with acute CNS insults, such as in ischemia or post-traumatic lesions, but also with neurodegenerative diseases such as ALS, Huntington's disease and Parkinson's disease. The neurotoxicity of EAA, referred...

Biologically active pentacyclic triterpenes and their current medicine signification

Jiří Patočka

J Appl Biomed 1:7-12, 2003 | DOI: 10.32725/jab.2003.002

Pentacyclic triterpenes are produced by arrangement of squalene epoxide. These compounds are extremely common and are found in most plants. There are at least 4000 known triterpenes. Many triterpenes occur freely but others occur as glycosides (saponins) or in special combined forms. Pentacyclic triterpenes have a wide spectrum of biological activities and some of them may be useful in medicine. The therapeutic potential of three pentacyclic triterpenes - lupeol, betuline and betulinic acid - is discussed in this paper. Betulinic acid especially is a very promising compound. This terpene seems to act by inducing apoptosis in cancer cells. Due to its...